成年人吸入性肺炎的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
成年人腹腔感染的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-治疗由拟杆菌属物种(包括脆弱拟杆菌),梭状芽孢杆菌属,大肠杆菌和克雷伯菌引起的腹腔内感染(例如腹腔脓肿,腹膜炎)
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
成人关节感染的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
骨髓炎通常的成人剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
成人腹膜炎的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠埃希菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌)引起的下呼吸道感染(如肺脓肿,肺炎),金黄色葡萄球菌(包括青霉素)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
成年人肺炎的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
成人细菌感染的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
成年人尿路感染的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱类杆菌),梭菌属物种,大肠杆菌,克雷伯菌属,黑球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
成年人皮肤和结构感染的常用剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-简单的感染包括皮肤感染,肺炎和尿路感染。
-高剂量感染包括坏疽性气体。
-对于涉及脓液的感染,应进行手术引流。
用途:
-治疗由金黄色葡萄球菌(包括产生青霉素酶的菌株)引起的骨骼和关节感染
-对由拟杆菌属(包括拟杆菌属),梭菌属,大肠杆菌和克雷伯菌属引起的腹腔内感染(例如腹腔脓肿,腹膜炎)的治疗
-治疗由拟杆菌属,大肠杆菌,流感嗜血杆菌,克雷伯菌,其他链球菌(不包括肠球菌,如粪肠球菌/链球菌),金黄色葡萄球菌(包括青霉素)引起的下呼吸道感染(如肺脓肿,肺炎)生产菌株)和肺炎链球菌
-治疗由拟杆菌属物种(包括脆弱的B型杆菌),梭菌属物种,大肠杆菌,克雷伯氏菌属,尼日尔球菌,肽链球菌属,变形杆菌,金黄色葡萄球菌(包括产生青霉素酶的菌株),表皮葡萄球菌,链球菌,链球菌引起的皮肤和结构感染和其他链球菌(不包括肠球菌,例如粪肠球菌/粪肠球菌)
-治疗由大肠杆菌,克雷伯氏菌属,摩根氏摩根氏菌,奇异变形杆菌,寻常变形杆菌和普罗维登斯菌种(包括普罗维登斯菌)引起的尿路感染
美国传染病学会(IDSA)建议:
每6至8个小时静脉注射1克
治疗时间:
-无残留感染组织的骨/关节感染(例如,截肢后):2至5天
-中度糖尿病足感染,包括残留的感染软组织(仅软组织):1至3周
-严重的糖尿病足感染(仅软组织):2至4周
-残留但可存活的骨头:4至6周
-无手术或术后残留残骨:3个月或更长时间
评论:患有糖尿病足感染的患者应开始胃肠外治疗,并在可能的情况下改用口服制剂。
用途:
-动物咬伤后的替代治疗
-预防性抗菌疗法可预防狗或猫咬伤的感染
-多杀性巴斯德氏菌引起的动物咬伤相关伤口的替代治疗
-由甲氧西林敏感金黄色葡萄球菌(MSSA),其他链球菌,肠杆菌科和/或专性厌氧菌引起的中度或重度糖尿病足感染的经验治疗
盆腔炎通常的成人剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-该药物对沙眼衣原体没有活性。
-可能由沙眼衣原体引起的盆腔炎患者应给予适当的抗衣原体治疗。
-对于涉及脓液的感染,应进行手术引流。
用途:治疗由拟杆菌属物种(包括脆弱的B杆菌),梭状芽孢杆菌属,大肠杆菌,淋病奈瑟菌(包括产生青霉素酶的菌株),黑霉菌,肽链球菌引起的妇科感染(例如子宫内膜炎,盆腔蜂窝织炎,盆腔炎)和无乳链球菌
美国疾病控制与预防中心(US CDC)建议:
肠胃外治疗:每6小时静脉注射2克PLUS IV /口服强力霉素和IV庆大霉素
-治疗时间:14天
替代性IM /口服治疗:每天口服2克IM ONCE PLUS丙磺舒口服ONCE PLUS强力霉素
-治疗时间:14天
评论:
-建议对输卵管卵巢脓肿的患者至少进行24小时住院观察。
-尚未评估该病的每日剂量;然而,它在类似条件下是有效的。
-口服治疗可在临床改善后的24至28小时内开始。
用途:建议辅助治疗沙眼衣原体,淋病奈瑟菌或人支原体引起的盆腔炎
子宫内膜炎的成人剂量
简单的感染(无/不太可能发生菌血症):每6至8小时静脉注射1克
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-该药物对沙眼衣原体没有活性。
-可能由沙眼衣原体引起的盆腔炎患者应给予适当的抗衣原体治疗。
-对于涉及脓液的感染,应进行手术引流。
用途:治疗由拟杆菌属物种(包括脆弱的B杆菌),梭状芽孢杆菌属,大肠杆菌,淋病奈瑟菌(包括产生青霉素酶的菌株),黑霉菌,肽链球菌引起的妇科感染(例如子宫内膜炎,盆腔蜂窝织炎,盆腔炎)和无乳链球菌
美国疾病控制与预防中心(US CDC)建议:
肠胃外治疗:每6小时静脉注射2克PLUS IV /口服强力霉素和IV庆大霉素
-治疗时间:14天
替代性IM /口服治疗:每天口服2克IM ONCE PLUS丙磺舒口服ONCE PLUS强力霉素
-治疗时间:14天
评论:
-建议对输卵管卵巢脓肿的患者至少进行24小时住院观察。
-尚未评估该病的每日剂量;然而,它在类似条件下是有效的。
-口服治疗可在临床改善后的24至28小时内开始。
用途:建议辅助治疗沙眼衣原体,淋病奈瑟菌或人支原体引起的盆腔炎
通常用于败血症的成人剂量
中度至重度感染:每4小时静脉注射1克或每6至8小时静脉注射2克
需要大剂量感染:每4小时静脉注射2克,或每6小时静脉注射3克
治疗时间:至少10天(A组溶血性链球菌感染)
评论:
-该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
-对于涉及脓液的感染,应进行手术引流。
用途:治疗由拟杆菌属物种(包括脆弱类杆菌),大肠杆菌,克雷伯菌属,金黄色葡萄球菌(包括产生青霉素酶的菌株)和肺炎链球菌引起的败血病
剖腹产通常的成人剂量
单剂量方案:脐带夹入后立即一次2克静脉注射
3剂治疗方案:每4个小时静脉注射2克,共3剂,一旦夹住脐带即给予,然后在初始剂量后4和8个小时给予
评论:该药物可以在3至5分钟内通过静脉注射或通过静脉输注给药。
用途:剖宫产患者的预防感染
通常用于外科手术的成人剂量
手术前30至60分钟静脉注射2克,首剂后每6小时注射2克
-治疗时间:24小时
评论:该药物可通过3至5分钟的静脉注射或通过静脉输注给药。
用途:在未受污染的胃肠外科手术或阴道子宫切除术的情况下,预防感染的患者
American Society of Health-System Pharmacists (ASHP), IDSA, Society for Healthcare Epidemiology of America (SHEA), and Surgical Infection Society (SIS) Recommendations :
2 grams IV ONCE
Comment: The recommended redosing interval from the initiation of the preoperative dose is 2 hours.
用途:
Recommended agent for surgical prophylaxis in patients who are undergoing the following procedures :
-阑尾切除术治疗单纯性阑尾炎
-Biliary tract (eg, elective high-risk, open procedure)
-结直肠
-Hysterectomy (abdominal/vaginal)
-Small intestine (eg, obstructed)
-Some urologic procedures (eg, clean-contaminated with entry into urinary tract)
Alternative agent for surgical prophylaxis in patients who are undergoing the following procedures :
-Open biliary tract procedures
Adjunctive agent (with metronidazole) for surgical prophylaxis in patients who are undergoing colon procedures
通常的成人剂量用于淋球菌感染-不复杂
US CDC recommendations :
Uncomplicated anorectal and urogenital gonococcal infections: 2 grams IM ONCE plus probenecid
评论:
-This regimen with probenecid is recommended if ceftriaxone is not an option.
-Doxycycline therapy for 7 days (if not pregnant) or single dose azithromycin is also recommended to treat possible concurrent chlamydial infection.
-The patient's sexual partner(s) should also be evaluated/treated.
Use: Treatment of uncomplicated gonococcal infections of the cervix, urethra, and rectum caused by N gonorrhoeae
腹腔感染的常用儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
关节感染的常用儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
骨髓炎通常的儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
腹膜炎的常用儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
肺炎的常规儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
败血症的常用儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
细菌感染的常用儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
尿路感染的常用儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empirical treatment for other gastrointestinal or genitourinary procedures in patients undergoing peritoneal dialysis
-Treatment of peritonitis
皮肤和结构感染的常用儿科剂量
3 months and older: 80 to 160 mg/kg IV per day, given in 4 to 6 equal doses
-Maximum dose: 12 grams/day
-Duration of therapy: At least 10 days (group A beta-hemolytic streptococcal infections)
评论:
-This drug may be given via IV injection over 3 to 5 minutes or via IV infusion.
-Higher doses should be used to treat severe or serious infections.
-Surgical drainage should be performed in infections involving collections of pus.
用途:
-Treatment of bone and joint infections caused by S aureus (including penicillinase-producing strains)
-Treatment of intraabdominal infections (eg, intraabdominal abscess, peritonitis) caused by Bacteroides species (including B fragilis), Clostridium species, E coli, and Klebsiella species
-Treatment of lower respiratory tract infections (eg, lung abscesses, pneumonia) caused by Bacteroides species, E coli, H influenzae, Klebsiella species, other streptococci (excluding enterococci, eg, E faecalis/S faecalis), S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of septicemia caused by Bacteroides species (including B fragilis), E coli, Klebsiella species, S aureus (including penicillinase-producing strains), and S pneumoniae
-Treatment of skin and structure infections cause by Bacteroides species (including B fragilis), Clostridium species, E coli, Klebsiella species, P niger, Peptostreptococcus species, P mirabilis, S aureus (including penicillinase-producing strains), S epidermidis, S pyogenes and other streptococci (excluding enterococci, eg, E faecalis/S faecalis)
-Treatment of urinary tract infections caused by Escherichia coli, Klebsiella species, M morganii, P mirabilis, P vulgaris, and Providencia species (including Providencia rettgeri)
美国儿科学会(AAP)建议:
Gestational age less than 32 weeks :
Postnatal age (PNA) 7 days or less: 35 mg/kg IV OR IM every 12 hours
PNA over 72 years: 35 mg/kg IV OR IM every 8 hours
Gestational age 32 weeks and older: 35 mg/kg IV OR IM every 8 hours
Pediatric patients beyond the newborn period: 80 to 160 mg/kg IV OR IM per day, given in divided doses 3 to 4 times a day
-Maximum dose: 12 grams/day
Neonates (72 hours) or older: 40 mg/kg IV ONCE with/without IV gentamicin
-Maximum dose: 3 grams/dose
用途:
-Treatment of ruptured viscus in traumatic wounds caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
-Treatment of ruptured viscus via colorectal or appendectomy caused by enteric gram-negative bacilli, Clostridium species, enterococci, and/or anaerobes (Bacteroides species)
国际腹膜透析学会(ISPD)建议:
PROPHYLAXIS: 30 to 40 mg/kg IV ONCE
-最大剂量:2克/剂量
Comment: Empirical doses should be given just prior to the procedure.
用途:
-Preferred empir